Carlos Marmol blew his third save of the season, allowing six runs in the ninth inning as the Houston Astros beat the Cubs 7-3 on Tuesday night.Without question, the Cubs worst loss of this two month old season so far. Robinson Cancel’s pinch-hit, two-run double tied the game and Michael Bourn singled in the go-ahead run off Marmol (1-2). Hunter Pence added a three-run shot for the Astros.Jordan Lyles tossed seven brilliant innings in his Major League debut, but committed a throwing error in the eighth which cost him a chance to earn his first big league victory.Fernando Rodriguez, Jr. (1-0) worked 1/3 of an inning to earn his first career win.