IOWA CITY—Mark Weisman and Akrum Wadley combined for 200 yards rushing and four touchdowns, leading Iowa to a 48-7 win over Northwestern on Saturday.The Hawkeyes, who have had a few injuries in the backfield, also got their first 100-yard rusher in 11 games. ”If we’re going to be any good, we have to run the ball effectively,” Ferentz said. ”The run game is all about detail and execution. I think we took a step forward today.” The Hawkeyes (6-2, 3-1 Big Ten) raced to a 24-0 lead in the first quarter and scored their most points in a conference game in almost nine years.Northwestern (3-5, 2-3) dropped its third straight game after being held to a season-low 180 yards of offense.Weisman and Wadley jolted Iowa’s running game that ranked 10th in the Big Ten entering Saturday’s game.Weisman rushed for a season-high 94 yards and three touchdowns. It was the senior’s fifth straight game with multiple scores. The bruising back’s 29 career touchdowns rank third on Iowa’s all-time list. ”It’s a mindset thing,” said Weisman, a Chicago native. ”We came out fired up and kept it going.This team has had the potential to do this kind of stuff all year, but we just weren’t executing. Today, we definitely executed.” Wadley ran for 106 yards and a touchdown in his first career game. The freshman was Iowa’s first 100-yard rusher in 11 games.Wadley provided an unexpected boost with Iowa’s Jordan Canzeri and LeShun Daniels sidelined due to injuries. The Hawkeyes lost a third running back, Jonathan Parker, on the opening kickoff. ”I’ve been having dreams about it, so when (Ferentz) told me to go in, I was like, `Wow, that’s crazy,”’ said Wadley, the first Hawkeyes player to rush for 100 yards in his debut since Brandon Wegher in 2009. Iowa quarterback Jake Rudock threw for 239 yards, including a pretty 31-yard fade to Tevaun Smith in the end zone.The Hawkeyes led 24-0 just 12 minutes into the game, using a stifling defense and an offense that clicked after being inconsistent the first half of the season.Iowa’s defense was simply too much for Northwestern, which had won six of the last nine in the series.The Hawkeyes recorded five sacks, scored off a blocked punt and recovered a fumble.