Jake Peavy’s one bad inning was enough to send the White Sox to a costly loss. Jason Kubel and Luke Hughes homered during Minnesota’s six-run first inning, and the Twins snapped the Southsider’s five-game winning streak with a 7-6 victory on Wednesday.Kubel and Hughes each hit a two-run shot off Peavy (6-7), who allowed four consecutive extra-base hits during his rocky beginning. Trevor Plouffe, Joe Mauer and Michael Cuddyer hit three straight doubles to plate the first two runs.The White Sox fell six games back of the AL Central-leading Tigers, who rallied for a 5-4 victory over Kansas City. The Sox are off Thursday and open an important three-game series at Detroit on Friday.There was a stout wind blowing out to left field on a hot afternoon at U.S. Cellular Field and Peavy said Minnesota’s ability to get the ball up into the breeze was the key to its strong start.The damaging streak of extra-base hits started with Plouffe’s one-out double. Mauer drove in Plouffe to give him 500 career RBI. Cuddyer then doubled in Mauer and scored when Kubel lofted a fly ball to left that got some help from the wind and barely cleared the outstretched glove of a leaping Juan Pierre.Kubel’s third homer in his last four games was his 14th in 39 career games at U.S. Cellular Field.After Danny Valencia struck out, Rene Tosoni singled and Hughes hit a drive to left-center for his seventh homer.Scott Diamond (1-2) allowed three runs and three hits in six innings to earn his first major league win. Manager Ron Gardenhire said Diamond may have learned from Peavy’s struggles.Joe Nathan yielded Paul Konerko’s two-run single in the ninth before finishing for his 12th save.Peavy settled down after the rough start, giving the White Sox a chance to get back into the game. Lillibridge hit a two-run homer in the third and came all the way around from first to score on Konerko’s double in the sixth.Peavy allowed six runs and eight hits over five innings, falling to 2-6 with a 5.77 ERA since a relief appearance on June 25. The 2007 NL Cy Young Award winner still isn’t 100 percent after having surgery on his right shoulder and said the bullpen outing might have been a mistake.Jason Repko added a two-out drive in the seventh for the Twins, who went 7-21 in August for the club’s worst-ever record in the month.Alex Rios hit an RBI single in the eighth but the Sox left the bases loaded when Tyler Flowers lined out to third to end the inning. The Sox mounted another challenge in the ninth, but Nathan struck out Rios with a runner on first to end the game.Ozzie Guillen had Adam Dunn hit for Lillibridge with runners on second and third in the ninth and the much-maligned slugger struck out swinging before Konerko’s bloop hit.Tough loss, but now it’s on to Detroit for what may be a season-turning series for the White Sox, one way or another.

NOTES—Carlos Quentin said his sprained left shoulder has improved but he wasn’t willing to put a timetable on his possible return. He’s been on the disabled list since Aug. 21….Twins 1B Justin Morneau (mild concussion symptoms) has to be cleared by the league before he can return. Morneau jammed his shoulder on Sunday and experienced headaches, prompting a concussion test….After a day off, the Twins begin a three-game road series against the Angels on Friday with Carl Pavano going against Los Angeles ace Jered Weaver….John Danks will start the series opener against Tigers ace Justin Verlander, who is 20-5. Verlander’s last loss came against the Sox on July 15